Abstract Search

ea0029p1825 | Thyroid cancer | ICEECE2012

Prognostic markers in Papillary Thyroid Cancer by immunohistochemistry

Castelblanco E. , Gallel P. , Martinez M. , Barrera L. , Capel I. , Moreno P. , Gimenez G. , Puig-Domingo M. , Bella R. , Porta M. , Halperin I. , Lopez S. , Orellana R. , Cameselle J. , Matias-Guiu X. , Mauricio D. , Robledo M. , Maravall J.

Papillary thyroid cancer (PTC) is the most common endocrine malignancy. Its management has not changed significantly in recent decades, and most patients receive the same treatment. Moreover, there are not alternative treatments for low response or aggressive neoplasias. The availability of reliable prognostic markers that would allow the PTC to be identified based on their aggressiveness at the time of diagnosis would derive in an individualized treatment. In a previous study...

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ea0011p809 | Thyroid | ECE2006

Study of the prevalence and mechanisms of action of TSH receptor and Gs protein alfa-subunit mutations, in toxic multinodular goiter and toxic adenoma from Galicia (Spain)

Palos F , Perez O , Alvarez-Iglesias V , Cameselle J , Barreiro F , Araujo D , Argueso R , Botana M , Cabezas JM , Dominguez L , Martinez T , Nuño J , Rueda JC , Lado-Abeal J

Toxic adenomas (TA) and toxic multinodular goiters (TMNG) are frequent causes of hyperthyroidism in Galicia, an endemic goiter area. In some European countries, 4080% of toxic goiters are caused by TSH receptor (TSHr) and Gs alfa-subunit (Gsa) mutations that activate cAMP pathway.Aims: To study 1) the prevalence of TSHr and Gsa mutations in TMNG and TA from Galicia, 2) the clonality of sequenced samples, 3) the constitutive activity of the identifi...

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Endocrine Abstracts

Prognostic markers in Papillary Thyroid Cancer by immunohistochemistry

Study of the prevalence and mechanisms of action of TSH receptor and Gs protein alfa-subunit mutations, in toxic multinodular goiter and toxic adenoma from Galicia (Spain)

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